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Overview of Immune System

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Overview of Immune System
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  • RINA
  • TINA
  • Pathogen
  • Danger ALERT!
  • Macrophages
  • A new pathogen entered our area. Take action !!
  • Macrophage
  • Antigen presenting cell
  • PATHOGEN
  • . .
  • Have to inform B-CELLS
  • . .
  • T-CELLS
  • Hand it over to us. We will destroy him.
  • . .
  • T-CELLS
  • Rina and Tina were having discussions about their college in a restaurant. Rina is suffering from viral infection. Due to lack of protection, the virus from Rina enters Tina's body through air when she coughs.
  • . .
  • . .
  • Have to kill this
  • Cytotoxic T-Cells
  • INSIDE RINA:The virus crosses the first line of defense in the mucus membranes via some chemical secretions and enters inside the body. Macrophages recognizes the incoming pathogen.
  • Cytokines
  • Cytotoxic T-Cells
  • Antigens are ingested and partially digested by macrophages. They are then presented to helper T cells by macrophages. This activates the T cells to release hormones that help B cells develop
  • PATHOGEN
  • Remember this pathogen and get ready if he returns again
  • VICTORY
  • Sure sir. We will produce Antibodies against him.
  • The activation of cytotoxic T cells is dependent on simultaneous interactions between molecules expressed on the surface of the T cell and molecules on the surface of the antigen-presenting cell
  • Helper T-Cell
  • Cytotoxic T cells can attack target cells that express antigens. Helper T-Cells also help activating more cytotoxic T cells and increasing its efficiency. They then stimulate B cells.
  • Helper T-Cell
  • Helper T cells activate B cells to produce antibodies that bind to and inactivate antigens. Memory B cells remember the same pathogen for faster antibody production in future infections.
  • Helper T-Cell
  • B CELLS
  • Memory B cell
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