DNA AND RNA REPLICATION
Snemalna Knjiga Besedilo
- Kate and liana was having a discussion on DNA and RNA virus replication , as they were having their exam on next day.
- All DNA viruses replicate in the nucleus, usinghost cell polymerases
- All RNA viruses replicate in the cytoplasm of the host cell, using virally-encoded polymerases.
- DNA - Enter the host cell's nucleus where the viral DNA is replicated.
- RNA is produced which moves into the host cell cytoplasm where viral proteins are produced.
- Replicated DNA strand remains hydrogen bonded to its template DNA strand. DNA require RNA primer to start replication.
- RNA virus attaches to the host cell and injects it's RNA virus into the host cell to initiate infection.The cell membrane of the host cells invaginates the virus particles , enclosing it in pinocytotic vacoule.
- There are no Okazaki fragments, both strands are synthesized in a continuous fashion.
- The infecting RNA virus produces messenger RNA. The mRNA is used to instruct the host cells to produce viral components .
- DNA polymerases cannot initiate synthesis de novo, they need a primer. In the case of adenovirus, the virally coded terminal protein (TP) acts as a primer. It is thus found covalently linked to the 5' end of all adenovirus DNA strands.
- new protein coats are produced inside the cell. Mature visions assemble within the cell.
- The replication strategy of a virus is generally dependent upon the type of nucleic acid genome it contains
- In RNA virus replication the Cell ruptures and release mature virus particles. These are the points to be known for DNA nd RNA virus replication.
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