Hans Christian Gram
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- Inventor of the Gram staining technique, Hans Christian Gram was the amazing biologist whose classification system led to research on about 30,000 species of bacteria.
- The Gram staining technique was created around the 1880s in Berlin, between Gram himself and German pathologist Carl Friedlander.
- The technique was devised by putting reagents onto bits of lung tissue, observing differences in the resulting coloration of various bacteria. The difference, he learned, was due to difference in the make of the bacterias' cell wall, hence the classification of gram positive and gram negative cells.
- Gram Staining 101
- The use of the Gram staining technique was most widely used from the 1940s to 1960s, but is still largely used today!
- Today Gram staining is instrumental in the search for new antibiotics. Tens of thousands of bacteria have been observed using this technique, including Teixobactin, a recently released antibiotic.
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- As amazing as the gram staining technique is, it is not without its faults. Gram himself stated in his publication that the technique is not perfect, but Gram expresses his hopes that other scientists will help refine the technique over time.
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