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- Hello. Is the appointment second time for the shingles vaccine?
- Yes. Also, can I get a brief explanation of a shingles?
- Sure. Shingles are a inflammation caused by a viruses that is same as a chicken pox. It can cause painful rash, so it is good to have a vaccine.
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- Next day...
- Hello, doctor. I got the second shot, but I don't know why I have sore arm, muscle aches, fever, and tiredness. Did I got sick?
- No, no you didn't get a disease. It is a type of humoral response.
- What is that?
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- 1st vaccine
- 2nd vaccine
- antigen
- macrophage
- helper T cell
- data
- data
- data
- memory B cell
- plasma cell
- x tons
- At the second shot, the first steps are same, but the memory B cells' data is used by plasma cells to create tons of antibodies. Then, antibodies find the antigen to stick, so the Leukocytes, mainly neutrophils can kill them.
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- At the first shot, the antigen that came by vaccine was eaten by macrophage to give the data to helper T cell, given to memory B cells to generate antibodies for the next time. This is nonspecific immunity.
- antibody
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