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PHAR222 Eliquis Storyboard

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PHAR222 Eliquis Storyboard
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  • Is this a new medication for you sir?Would you like me to provide you with some informationn?
  • Yes this is a new medication and I would appreciate some information my good sir.
  • Eliquis is an anticoagulant or blood thinner used for the prevention of stroke and systemic embolisms for patients with atrial fibrillation also known as a fast and irregular heart rhythm.
  • Atrial fibrillation increases your risk of forming blood clots increasing your risk of stroke due to blood clots or a pulmonary embolism clot breaking free and travelling through the blood stream to the lungs or rest of the body such as the brain or heart.
  • 00:00-00.10 - Interaction between pharmacist and patient - new medication so information offered and accepted.
  • Eliquis is also used in patients that have recently had hip or knee replacement surgery to help in the prevention of blood clot formation.
  • 00:10-00:20 - Pharmacist begins to describe Apixaban and indications.
  • The recommended dosage varies on what you are using this medication specifically for but for atrial fibrillation, the dosage is 5mg twice daily.
  • How much and often do I take this medication?
  • 00:20-00:50 - Pharmacist continues to explain basic pathophysiology of the diseases involved with treatment of Apixaban.
  • Are there any side effects I should be aware of?
  • 00:50-01:00 - Pharmacist continues talking.
  • Eliquis is generally well-tolerated with the most common side effect being bleeding.
  • 01:00-01:15 - Patient asks Pharmacist for dosage guidelines and Pharmacist responds.
  • 01:15-01.20 - Patient queries Pharmacist on side effects associated with Apixaban.
  • Yes I am, I take Nurofen occasionally for my bad knee and St Johns Wort
  • 01:20-02:20 - Pharmacist explains common side effects and signs of bleeding.
  • Some potential signs of bleeding are red, pink or brown urine, red or black stools (look like tar), coughing up or vomiting blood (looks like coffee grounds), headaches, dizziness, frequent nose bleeds and/or heavier than normal menstruation.
  • 02:20-03:00 - Pharmacist explains more severe symptoms to notify your doctor about if you experience them.
  • However notify your doctor immediately if you notice any of the following: nausea/vomiting, diarrhoea or constipation, bruising, tiredness, bleeding from any part of the body no matter how minor and frequent need to urinate/pain when urinating.
  • 03:00-03:20 - Pharmacist asks patient if they are taking any other prescription or OTC medications and patient responds.
  • Are you taking any other prescribed or OTC medications currently?
  • When it comes to drug interactions, the first one on the list is medicines used to treat pain and inflammation such as NSAIDs or aspirin because these drugs increase the risk of bleeding and other blood thinners such as warfarin.
  • The second interaction occurs between Eliquis and the natural supplement, St Johns Wort. St Johns Wort tends to cause an increase in the enzyme that breaks down Eliquis decreasing the effectiveness. You should talk to your doctor before taking any more of this supplement.
  • Have I answered all your queries today sir, regarding the drug Eliquis?
  • Yes, thank you so much for the information.
  • 03:20-03:40 - Pharmacist explains interactions with NSAIDs and its significance.
  • I'm curious, how does Eliquis actually work within the body?
  • 03:40-04:00 - Pharmacist explains interaction with St Johns Wort and refers to doctor.
  • Apixaban is a reversible, direct and highly selective inhibitor of Factor Xa (FXa), which is an enzyme that plays an essential role in the formation of blood clots. Apixaban indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, it prevents thrombin generation and development, prolonging clotting time.
  • 04:00-04.10 - Completion of transaction between Pharmacist and patient.
  • Oh wow thats so interesting! Thanks for the explanation.
  • 04:10-04:20 - Pharmacy student approaches Pharmacist and questions the mechanism of Apixaban.
  • 04:20-05:00 - Pharmacist explains the mechanism of action of Apixaban.
  • 05:00-05:10 - Pharmacy student and Pharmacist end interaction.
  • Australasian Society of, C., Experimental, P., Toxicologists,Pharmaceutical Society of, A., & Royal Australian College of General, P.Australian medicines handbook. Australianmedicines handbook : AMH. Medicines, M. O. (2013). Apixaban (Eliquis), dabigatran (Pradaxa)and rivaroxaban (Xarelto): Information for consumers. Ward, C., Conner, G., Donnan, G., Gallus, A., & McRae, S. (2013).Practical management of patients on apixaban: a consensus guide. Thrombosis journal, 11(1), 27. https://www.emims.com.au/Australia/drug/info/Eliquis/Eliquis?type=full#Indicationshttps://www.nhlbi.nih.gov/health-topics/venous-thromboembolism#:~:text=Venous%20thromboembolism%20(VTE)%20is%20a,leg%2C%20thigh%2C%20or%20pelvis.https://www.emims.com.au/Australia/drug/info/Eliquis/Eliquis?type=full#Pharmacodynamics
  • 05:10-05:15 - Scene fades out to black.
  • 05:15-05:20 - Disclaimer
  • This video is for informational purposes only and is not intended to be substitute for medical advice from your general practitioner. Always follow instructions provided to you by your local healthcare provider.
  • 05:20-05:25 - References
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