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  • Hmmm...
  • Could catching cow pox prevent people from catching small pox?
  • I think I can stop you from ever getting smallpox! It won't hurt...much!
  • OH NO!
  • Edward Jenner, an expect on cuckoos was also a good scientist and he really wanted to conquer the deadly smallpox. One day, he observed Sarah Nelmes, an ordinary milkmaid get infected by cow pox.
  • Noting the common observation that milkmaids were generally immune to smallpox, Jenner suggested that the pus in the blisters that milkmaids received from cowpox protected them from smallpox.
  • Jenner tested his hypothesis by inoculating James Phipps, an eight-year-old boy. He scraped pus from cowpox blisters on the hands of Sarah Nelmes
  • VaccinaDear the British government,The initial source of infection was a disease of horses, called "the grease", which was transferred to cattle by farm workers, transformed, and then manifested as cowpox. If variolation after infection with cowpox fails to produce a smallpox infection, immunity to smallpox has been achieved.Dr. Edward Jenner
  • Jenner inoculated Phipps in both arms that day, subsequently producing in Phipps a fever and some uneasiness, but no full-blown infection.
  • Later, he injected Phipps with variolous material, but no disease followed. The boy was later challenged with variolous material and again showed no sign of infection.
  • Eventually, vaccination was accepted, and in 1840, the British government banned variolation – the use of smallpox to induce immunity – and provided vaccination using cowpox free of charge.
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