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AP
An AP opens the Ca2+ channels on the membrane of the neuron's synaptic terminal
Ca2+
Ca2+ Channel
Ca2+ from the synaptic terminal diffuses into the neuron
Synaptic Terminal
Ca2+
Neuron
ACh is released from the synaptic vesicles
ACh
Synaptic Vesicle
A robber (AP) busts a thief (Ca2+) out of his cell (Ca2+ channel) within jail (synaptic terminal).
ACh binds to Na+ channels on the sarcolemma
ACh
Na+ Channel
The thief (Ca2+) runs from jail (synaptic terminal) into the city (neuron)
An AP is generated and moves down the sarcolemma into the t-tubules
APs Spreading
The ringleader (ACh), senses that time is right, and breaks out of Alcatraz (synaptic vesicles), where he was being held
The AP allows Ca2+ channels to open and release Ca2+
Ca2+ Channel
Ca2+
Ca2+
The ringleader (ACh) then opens up other jails (Na+ channels) around the city (sarcolemma)
As a result, a massive wave of crime (AP) blankets the city (Sarcolemma t-tubules)
This wave of crime (AP) empowers other thieves (Ca2+) to break out of their cells (Ca2+ channels) in the city jail (TC SR)
Ca2+ Channel
Ca2+
Ca2+
Ca2+ Channel
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