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  • Dia: 1
  • Hello. Is the appointment second time for the shingles vaccine?
  • Yes. Also, can I get a brief explanation of a shingles?
  • Sure. Shingles are a inflammation caused by a viruses that is same as a chicken pox. It can cause painful rash, so it is good to have a vaccine.
  • Dia: 2
  • Next day...
  • Hello, doctor. I got the second shot, but I don't know why I have sore arm, muscle aches, fever, and tiredness. Did I got sick?
  • No, no you didn't get a disease. It is a type of humoral response.
  • What is that?
  • Dia: 3
  • 1st vaccine
  • 2nd vaccine
  • antigen
  • macrophage
  • helper T cell
  • data
  • data
  • data
  • memory B cell
  • plasma cell
  • x tons
  • At the second shot, the first steps are same, but the memory B cells' data is used by plasma cells to create tons of antibodies. Then, antibodies find the antigen to stick, so the Leukocytes, mainly neutrophils can kill them.
  • Dia: 0
  • At the first shot, the antigen that came by vaccine was eaten by macrophage to give the data to helper T cell, given to memory B cells to generate antibodies for the next time. This is nonspecific immunity.
  • antibody
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