In biological processes, ATP is the energy currency. ADP releases energy and ATP stores it.The catabolic pathways that break down energy-rich substances to create ATP are part of cellular respiration.The thousands of reactions that occur during cellular respiration are summarised in the equation below:C6H12O6(s) + 6O2(g) 6CO 🡪 2(g) + 6H2O(l) +ATP
YAY! Now ATP can be made by breaking down the energy-rich compounds that were just consumed
6 carbon SugarC-C-C-C-C-C
1. Glycolysis
Glucose
Cytoplasm
(2) ADP + P
(2) NAD+
(2) NADH
(2) ATP
Occurs in CytoplasmUses 2 ATP, creates 4 reduces 2 NAD+ to 2 NADHDoesn't require O2Breakdown of Glucose into 2 Pyruvate Molecules
Occurs in the mitochondrial matrixFor 1 Pyruvate has 1C is removedReleases 1 molecule of CO2 Becomes 2C compound1 molecule of NADH is formed (per 1 Pyruvate)Acetyl group attaches to CoA which forms the Acetyl coenzyme A
Pyruvate + NAD++ CoA → Acetyl-CoA + NADH + CO2 + H+
Pyruvate3 carbon moleculesC-C-C
Transport Protein
NAD+
CO2
Coenzyme A (CoA)
NADH + H+
Acetyl- CoA
FADH2
NADH
FAD+
The Krebs Cycle is requires oxygen to process.
NAD+
3. Krebs Cycle
ATP
Acetyl CoA
CoA
CoA
NAD+
NADH + CO2
NAD+
Carbon
NADH + CO2
Occurs in the mitochondrial matrixCoA separates from 2-carbon, forming a 6C molecule.One CO2 is produced when two C are oxidized (2 are created due to two Acytle CoA)NAD+ captures electrons from oxidation, resulting in NADH (1 per CO2)There is a release of 1 ATP and 1 FADH.After 2 cycles:4 CO26 NADH2 FADH2 ATP
Electron Transport Carriers
All of the electron carriers, as well as NADH and FADH, are utilized here.While transferring electrons through proteins, NADH offers 3 H and FADH gives 2 H+.H+ diffuses into the gap between the inner and outer membranes, forming a gradient.ADP →ATP, electrons are exchanged between proteins.The electron reaches the final acceptor, O2, which forms H2O with the help of H from ATP synthase.Electron carriers are molecules that transfer electrons while also storing energy for a short period of time.
(Khan Academy, 2016)
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