Homeostasis pt 2
Testo Storyboard
- Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
- MyoDMyf5
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- Undoing the Damage: Anti-inflammatory responseNegative feedback systemStimulus : Cytokines released by M1 MacrophagesSensor: Nerve cells in the skin & brainControl : White blood cells (Monocytes)Organ systems involved : lymphatic, musculoskeletal, nervous systemEffector: M2 Macrophages
- M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
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- M2
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- Undoing the Damage: Repairing Muscle FibreNegative feedback systemStimulus : M2 MacrophageSensor: Nerve cells in the skin & brainOrgan systems involved : lymphatic, musculoskeletal, nervous systemControl: Satellite CellsEffector: Satellite Cells
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- M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
- M2
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- Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
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