Hi! Based on our examination from your genetic, your condition is related to your cell respiration.
Let me explain it.
Cellular respiration is the process in our body in which cells break down glucose, release the stored energy, and use it to make ATP.
Yes yes! We tackled that in our BioChem lecture.
It occurs in three stages: Glycolysis, Krebs Cycle, and Electron Transport Chain.
Yes that's right! It takes little ATP itself to get this process started. This resulted 2 ATP and 2 NADH, converted from NAD+, a coenzyme that have the ability to transfer electrons.
In the presence of oxygen, pyruvate is converted into acetyl CoA which contributes another 2 NADH before Krebs get started.
Glycolysis breaks down glucose into two molecules of pyruvate which occur in the cell's cytoplasm.
Then, the next stage is Krebs or Citric Acid Cycle which occurs in the mitochondria and requires oxygen in the process.
You're listening well to your teacher! That's right! The acetyl CoA will then be oxidized and carbon dioxide is produced and will be released as a waste product.
This process completes the breakdown of glucose and 2ATP, 6 NADH, 2FADH2 are also produced.
It also requires oxygen and this process is still in the mitochondria.
Yes, you're correct! Electrons are transferred from the NADH and FADH2 to several electron carriers. Through this, proton gradient is created that are used to power ATP synthase.
The third and last stage is the Electron Transport Chain (ETC).
The ATP synthase, an enzyme, takes phosphate and adds them to ADP. Then, ATP is made. Right, Doctor?
Yes, yes! You're smart! Oxygen is the final acceptor of the electrons. When oxygen combines with two protons, water is formed (also a waste product).