Unknown Story
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- PrognosisThe average life span for people with CF who live to adulthood isabout 44 years.There are no limitations to their exercise, diet, or activities. However, due to the different lung infections that they can get, they should not meet or talk with other patients with CF in-person.Parents of children with cystic fibrosis are more likely to experience anxiety, depression, or both compared to parents in general.
- Treatments/Medications
- antibiotics to prevent and treat chest infectionsmedicines to make the sticky mucus in the lungs thinnera medicine called ivacaftor to help reduce the levels of mucus in the body – although this is only suitable for fewer than 1 in every 20 people (4%) with cystic fibrosisbronchodilators to widen the airways and help make breathing easiersteroid medication to treat nasal polyps (small growths inside the nose)
- Current Research
- Instead of trying to correct the protein or do gene therapy, Martin D. Burke is using a small molecule surrogate that can perform the channel function of the missing or defective protein. In their studies, the researchers used lung tissue from patients with cystic fibrosis, as well as pig models of cystic fibrosis, and found that amphotericin spurred a host of changes associated with improved lung function — restoration of pH levels, improved viscosity, and increased antibacterial activity, among others.
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