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  • Got it!
  • Since there is no oxygen in the cell, moreNAD+ is needed to keep the glycolysis going.
  • In the absence of oxygen the pyruvate's formed through glycolysis are rerouted to a stage called fermentation!
  • Fermentation frees up some NAD+ which creates by products like... Lactic acid! which is what you were feeling after lifting weights.
  • Oh and by the way, glycolysis is an anaerobic process which means it doesn't require oxygen.
  • So basically your telling me that my muscles usedup all the oxygen they had, and had to kick into anaerobic respiration in order to get the energy that I needed?
  • The Krebs cycle takes the products of glycolysis, (which were those carbon rich pyruvate's,) and reworks them to create another two ATP molecules. the 2 pyruvate are oxidized and converted to 2 acetyl CoA.
  • Now the Krebs cycle takes place inside the inner membrane of the Mitochondria.
  • Yes! The Krebs cycle and the electron transport chain are a little different because they are aerobic processes. Which means they require oxygen!
  • Oh!
  • The addition of hydrogen turns NAD into NAD+ and turns FAD to FADH2.
  • In a way, NAD's and FAD's are kind of like batteries. They pick up hydrogen's and energized electrons from the pyruvate's and charges them up!
  • Oh I forgot to mention that the Krebs cycle is often also called the citric acid cycle because of the by product of citric acid.
  • Woah...
  • These proteins swap these electrons to send hydrogen protons from inside the very center of the mitochondria across its inner membrane to the outer compartment of the mitochondria.
  • Now all the NADH's and FADH2's that we made in the Krebs cycle,their electrons are going to provide the energy that will pump along a chain of channel proteins, across the inner membrane of the mitochondria, where the Krebs cycle occurred.
  • And viola! that's basically why you have the energy you do!
  • And so, these protons are allowed back in through a special protein called ATP synthase
  • However once they are out, the protons want to get back to the other side of the inner membrane, because as we know, nature always seeks to reach the equilibrium.
  • That's really insane! I can't believe our bodies go through all that just to make energy for our selves.
  • Well in that case I think i'll just try to use as little energy as possible and just sit here forever.
  • Hahaha! Good luck with that one!
  • Yep! It's a very complex but necessary process for sure.
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