Duncan's heirs come back to overthrow Macbeth.
Lady Macbeth begins to hallucinate, believing she has physical blood stains on her hands....
By the end of the play, Macbeth is faced with the united armies of Scotland, led by Macduff.
CHARACTER vs CHARACTER
CHARACTER vs SELF
CHARACTER vs SOCIETY
...why won't these wash off?
That Macbeth has become a total weirdo and tyrant!
...the throne is rightfully ours!