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- Yes, of course. Well, we now know that there are four structural proteinsfound in SARS-CoV-2. I’ve projected a few pictures of the structure of the virus. The capsid outside the genome is created by the nucleocapsid protein, and the genome is further packed by an envelope made up of three structural proteins: M protein, S protein and E protein. The spike glycoprotein mediates coronavirusentry into host cells (S protein). and it is a desirable antiviral target.
- S protein is made up of two functional subunits, S1 and S2. The S1 subunit is made up of an N-terminal domain (NTD) and a receptor binding domain (RBD). The S1 subunit's function is to bind to the host cell's receptor.
- What is the classification of sars cov 2, sir Asdren?
- The S2 subunit contains the fusion peptide (FP), heptad repeat 1 (HR1), central helix (CH), connector domain (CD), heptad repeat 2 (HR2), transmembrane domain (TM), and cytoplasmic tail (CT). The S2 subunit's function is to connect the membranes of viruses and host cells. The S1/S2 protease cleavage site is located on the border between the S1 and S2 subunits. Is everyone clear at this point?
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